| I-64 East EXITS: 45 - Nitro 47 - Cross Lanes 50 - Institute 53 - Dunbar 54 - So. Charleston - MacCorkle 56 - So. Charleston - Montrose 58a - Charleston - Oakwood Rd. 58b - Charleston - Virginia St. 58c - Charleston - Lee St. 59 - I-77 / I-79 |
| I-64 West EXITS: 45 - Nitro 44 - St. Albans 40 - Scott Depot 39 - Teays Valley 34 - Hurricane - St. Rt. 34 28 - Milton - US Rt. 60 20 - Barboursville - Mall 18 - Barboursville - US Rt. 60 15 - Huntington - 29th St. 11 - Huntington - Hal Greer Blvd 8 - Huntington - 5th Street E 6 - Huntington - US 52 N 1 - Ceredo / Kenova - US 52 S Kentucky State Line |
| Rt. 25 South: Institute Dunbar North Charleston Charleston |
| Rt. 62 North: Poca Raymond City Black Betsy Bancroft Plymouth Hometown Red House Eleanor Buffalo |
| Rt. 60 West: St. Albans Hurricane Culloden Milton Ona Barboursville Huntington Kentucky State Line |
| Rt. 60 East: St. Albans Spring Hill So. Charleston Charleston Kanawha City Rand Dupont City Malden |
| Destination Miles: Columbus 149 Cincinnati 198 Pittsburgh 241 Cleveland 265 Charlotte 279 |
| Destination Miles: Indianapolis 299 Washington DC 372 Virginia Beach 435 Myrtle Beach 466 Atlanta 518 |